Day with out phone Essay Example | Topics and Well Written Essays - 750 words

Day with out phone - Essay Example According to a study conducted by Nokia in 2010, the average person checks phone 150 times per day. Considering that mobile industry has changed significantly over the last two years and mobile phones have more features, there is a possibility that an average person checks phone more often than the situation was in 2010 (Ling and Scott 22). Mobile phones have changed dramatically particularly with the invention of smart phones. As a result, mobile phones have become pocket-sized, powerful, and irreplaceable tools in human life. People are increasingly relying on their mobile phones handset in performing a set of tasks. Since smart phones have more advanced features and applications than the previous phones, they automate processes that would have previously required users to use computer. Users of smart phones can do many things that could have only been done using computer in the past. Apart from using smart phones to perform tasks, users also use them for entertainment purposes (Li ng and Scott 10). In the light of the uses of mobile phone in modern times, staying away from it for only a day is unimaginable and a cringing thought. While at first it may make one feel liberated and free from the oppressive nature of a never-ending notifications influx that constantly pull people’s attention from the real world, it may not take long before one realizes how indispensable tool it is (Obeidallah para 10). A former attorney who turned to be a political comedian, Dean Obeidallah wrote a piece in CNN titled â€Å"A Day without a Cell phone† where he explained how one can tend in such a situation. In the piece, Dean noted that a day without a phone gave him an opportunity to actually have a real look at his surroundings, an opportunity he would otherwise not have had if he had a phone (Obeidallah para 11). As noted by Dean and an observation that can be shared by majority of people is that a day without a phone saves one the stress that

Synthesis of API’s and API’s based Derivative

Synthesis of API’s and API’s based Derivative Title of Proposed Project: Efficient synthesis of API’s and API’s based Derivative for their Structure Activity Relationship and Pharmacokinetics Profile Project Details Project Summary This project concern with the establishment of organic synthesis facilities in Department of Chemistry, UNIVERSITY OF KARACHI. The established facilities will be used for the training of BS/M.Sc./MS/M.Phil. And Ph.D. scholars in the field of Organic Synthesis. In this project we will focus on the establishment of synthetic organic laboratory, the synthesis of the two API’s (Secnidazole Atenolol). We are requiring the following basic facilities which we want to establish by this research project. Facilities required for: Organic Synthesis Fuming HOODs for save, non-hazardous and smooth working at the moment. Inert atmosphere working conditions since many organic reactions requires inert condition. Safety equipment’s i.e. firefighting equipment’s, washing shower in case of chemical accident and first aid facilities. (UPS) as regular power breakdown results in the unsuccessful reactions and causing faults in the electronic instruments. UV lamp as processing of many reaction monitor under UV light. Rotary evaporator Partial availability of glass wares. MAS-II Microwave workstation for repaid synthesis of APIs. Proposed Goals / Objectives Hypothesis / Basis of research The purpose of this project is to setup a laboratory which can design (Organic Synthesis) and synthesize (Organic Synthesis) the APIs for the local Pharmaceutical industry along with the establishment of the required facilities. The following APIs will be synthesized. ATENOLOL Efficient Synthesis of Atenolol. Synthesis of Atenolol based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile SECNIDAZOLE Efficient Synthesis of Secnidazole Synthesis of Secnidazole based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile Goals / Objectives Boost up economy of Pakistan Synthetic solution for local industry. Provide sufficient amount of these drugs to common people. INTRODUCTION API stands for active pharmaceutical ingredients and its covers a lot of pharmaceutically active compounds which has great importance in industry as well as to common people as the insufficiency of these drugs causes hundreds of death. Due to the importance of API we decided to work with the synthesis of API as it will create the impact of API research on national level. The synthesis of API could decrease the import bill of such active ingredient in Pakistan and also opens the opportunity of job. This project could provide a platform to save the foreign currency reserves and supply sufficient amount of drugs to common people at low cost. Ours Efforts will be enabling to purpose the more efficient synthesis of complex molecules. In this project we have design the synthesis of the following APIs ATENOLOL Efficient Synthesis of Atenolol. Synthesis of Atenolol based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile SECNIDAZOLE Efficient Synthesis of Secnidazole Synthesis of Secnidazole based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile 4a) Background of the Research Problems to be addressed Secnidazole (Part: A) Efficient Synthesis of Secnidazole Secnidazole is a molecule which belongs to the class of 5-nitroimidazole and it is considerably more effective than other imidazole drugs. It is the important API required for the local industry. However it has been used for the treatment of amoebiasis, giardiasis, urogenital trichomoniasis and nonspecific bacterial vaginosis and also a gel formulation of secnidazole was developed for the treatment of periodontitis. . All nitroimidazoles are synthetic drugs such as metronidazole. Tinidazole, dimetridazole, secnidazole and ornidazole. Among all these we selected secnidazole because of its High efficacy. Secinidazole is the mainly use for antiprotozoal activity and its single dose possess three days anti protozoal activity. Figure 1: Chemical Structure IUPAC Name:1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2-ol Figure 2: Proposed Two-Step Synthesis route for Secnidazole After observing the reaction condition and UV-Vis absorption, FTIR, ESI-MS and NMR results. The purposed scheme will be optimized. Synthesis of Secnidazole based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile Pharmacological and pharmacokinetic properties of existing drugs can be enhanced by chemical modifications. A prodrug (drug transporter) formation is a great approach to improve and modify the physio chemical properties of the drug, boost up its concentration at the site of action, extend its period of action and decrease its toxicity. Regarding 5–7% of drugs approved worldwide are categorized as prodrug. Prodrugs are the reversible, inactive or less active derivatives of a drug. Prodrugs are hydrolyzed either by enzymatically or non-enzymatically to discharge parent drug while the co-drugs (mutual prodrug) are the special type of prodrug in which two or more pharmacologically active pro moieties exist via chemical bond to release two or more parent drugs upon the cleavage of bond by enzymatically or chemically. The variety of chemical linkages used in the formation of Prodrugs. Although the ester formation is common followed by imides, amide and carbamate derivative. Thatâ₠¬â„¢s why in this project our aim is to synthesize the prodrug for its better mode of action and their structure activity relationship and their pharmacokinetics profile. ATENOLOL (Part: B) Efficient Synthesis of Atenolol Atenolol (ATN) belongs to the class of drug called beta-blockers. Beta-blockers (beta adrenoreceptor antagonists) are basically competitive inhibitor that’s inhibits the action of stimulating hormones on beta adrenergic receptors in the nervous system. Atenolol works by competing for receptors sites on cardiac muscle. This slow down the strength of heart‘s contractions and reduce its oxygen requirements and the volume of blood it has to pump. Atenolol is one of the extensive used active pharmaceutical ingredients (API) for the treatment of Hypertension, myocardial infarction (Heart attack), Arrhythmias (rhythms disorder), Angina (chest pain) and disorder arising from decreased circulation of blood. Figure 1: Chemical Structure IUPAC Name:2-[4-[2-hydroxy-3-(propan-2-ylamino) propoxy] phenyl] acetamide Figure 2: Proposed Two-Step Synthesis route for Atenolol The stereochemistry is important for any molecules. In atenolol (S) isomer is important for its activity the opposite (R) enantiomer may be responsible for the side effects. There have been considerable efforts done in the preparation of enantiomerically pure(S) confirmation Synthesis of Atenolol based derivatives for Structure-Activity Relationship Studies (SARS) and their pharmacokinetics profile On the basis of the importance of prodrug (mention above part) our aim is to synthesize the prodrug for its better mode of action and their structure activity relationship and their pharmacokinetics profile. 4B.RESEARCH PLAN/ METHODOLOGY: SCHEDULE/PHASING Establishment of Organic Synthesis Facilities: In the starting 1st months of this project all the basic and reaction requirement apparatus and glassware will be installing. Efficient Synthesis of SECNIDAZOLE: After initialization, the starting 3 months will be utilized on the proposed and modified efficient synthesis of Secnidazole to get the maximum yield of required API at minimum cost. Synthesis of SECNIDAZOLE based derivatives for SARS: In the 5th and 6th month modification on the molecule of Secnidazole will be applied and study their pharmacokinetics profile Synthesis of ATENOLOL: In the period of 7th to 9th month of the project efficient synthesis of atenolol will be done Synthesis of ATENOLOL based derivatives for SARS: In the period of 10th to 11th month of the project timeline, derivatization of atenolol will be carried out and studied their pharmacokinetics profile Summarize results and expand to new project: At the end month of this project timeline a final project report will be submitted along with findings. Also discuss the achievements and problems faced during this project. 4c) References Secnidazole (Part: A) Larina, Lyudmila, and Valentin Lopyrev.Nitroazoles: synthesis, structure and applications. New York: Springer, 2009. Crozet, Maxime D., Cà ©line Botta, Monique Gasquet, Christophe Curti, Vincent Rà ©musat, Sà ©bastien Hutter, Olivier Chapelle, Nadine Azas, Michel De Mà ©o, and Patrice Vanelle. Lowering of 5-nitroimidazoles mutagenicity: towards optimal antiparasitic pharmacophore.European journal of medicinal chemistry44, no. 2 (2009): 653-659 Wang, She-Feng, Yong Yin, Fang Qiao, Xun Wu, Shao Sha, Li Zhang, and Hai-Liang Zhu. Synthesis, molecular docking and biological evaluation of metronidazole derivatives containing piperazine skeleton as potential antibacterial agents.Bioorganic medicinal chemistry22, no. 8 (2014): 2409-2415. Samanta, Himadri Sekhar, and Samit Kumar Ray. Controlled release of tinidazole and theophylline from chitosan based composite hydrogels.Carbohydrate polymers106 (2014): 109-120. Elias, P. cureforneedy.com 2009, 1-11. Shahid, Hafiz Abdullah, Ejaz Hussain, Sajid Jahangir, and Sammer Yousuf. 1-(2-Methyl-5-nitro-1H-imidazol-1-yl) propan-2-yl acetate.Acta Crystallographica Section E: Structure Reports Online70, no. 3 (2014): o294-o294. Atenolol (Part: B) Chaudhari, Vilas, Syed Hussain, and Milind Ubale. International Journal of Chemical Studies. Kitaori, Kazuhiro, Yoshikazu TAKEHIRA, Yoshiro FURUKAWA, Hiroshi YOSHIMOTO, and Junzo OTERA. A practical synthesis of optically active atenolol from chiral epichlorohydrin.Chemical and pharmaceutical bulletin45, no. 2 (1997): 412-414. Darnle, Subhash V., Prashant N. Patil, and Manikrao M. Salunkhe. Chemoenzymatic synthesis of (R)-and (S)-atenolol and propranolol employing lipase catalyzed enantioselective esterification and hydrolysis.Synthetic communications29, no. 22 (1999): 3855-3862 IMPACT OF PROPOSED RESEARCH The impact of this project will boost up the economy of Pakistan and will decrease the import bill of Pakistan and also increases the exportation. The project also aims to train the man power and create the skillful hand that can provide the better solution to our local industry. This project also creates the networking between the local industry and researcher. This project also contributes in the providing of the medicine to common people at minimum cost. Estimated Budget For The Proposed Research Period: DESCRIPTION PER YEAR Amount (in million Rs) A. Salaries and Honorarium PI: One Month/Year of Basic Pay @ 104000 0.104 (208000) Student Ships @ 20,000.00 per month (two) 480000 0.48 (480000) Secretariat Staff Part-time Lab Attendant @ 1500 PM 18000 0.018 (18000) Subtotal: (A) 602000 0.602 (602000) B. Permanent Equipment General purpose fume hood @ Pkr 150,000/= (two) 300000 0.600 (600000) The rotary evaporator  ® r 3 focuses and accessories @ Pkr 1500000 1500000 1.500 (1500000) Jacketed reaction apparatus @ Pkr 169650/= (one) 169650 0.1695 (169650) Glassware, hotplates, stirrer, etc. 250000 0.250 (250000) Laptop (dell core 2i) 50000 0.050 (50000) General lab update i.e. Ups and power supply solutions 250000 0.250 (250000) Mas II: microwave synthesis system @ $8000/= (one) 800000 0.800 (800000) Subtotal: (B) 3319650 3.319650 (3319650) C. Expendable Supplies Chemicals and solvents 300000 0.300 (300000) General lab expenditures 100000 0.100 (100000) Spectroscopy techniques 250000 0.250 (250000) Subtotal: (C) 650000 0.65 (650000) D. Others (Literature, documentation, information, online literature search, contingencies, postage, Local Travel Miscellaneous etc). Journal Publication Fee / Online Material (up to Rs.50,000) 50000 0.050 (50000) Stationary/Contingency (10,000/- per year) 10000 0.010 (10000) Participation in local conferences, workshops and winter summer schools by PI and students 10000 0.010 (10000) Audit Fee (Max. Rs 10,000) 10000 0.010 (10000) Accountant Fee (Max. Rs. 10,000) 10000 0.010 (10000) Subtotal: (D) 90000 0.090 (90000) Grand Total (A + B + C + D): 4661650 4.661650 (4661650) JUSTIFICATION Salaries Allowances Two Studentships @ 20,000.00 per month (PM): It is very necessary that at least two full time studentships available to students so that students can perform their work with piece of mind so that they have no need to sort part time jobs to meet their day to day expense Part-time Lab Attendant @ 1500 PM: During period of project operations different kind of tasks are assigned to Lab Attendant in addition to their normal job responsibilities. Therefore it is justified to compensate their work with an honorarium. Permanent Equipment: The Rotary Evaporator and accessories (one): Many organic reactions are in liquid phase and require much more time to evaporate on room temperature that’s why to save time and fast reaction process need rotary evaporator. General Purpose Fume Hood: As many organic reaction, chemicals and solvents are hazardous to human health. For safety and precautionary step need two fuming hoods Jacketed Reaction Apparatus: It is the temperature control apparatus. As many reaction are temperature dependent and monitor through varying temperature. to make reaction efficient we need jacketed reaction apparatus Glassware, Hotplates, Stirrer, refwork etc: These are the basics requirement for organic synthesis as well as we have shortage of these basics needs that’s why we need these General lab updates i.e. UPS and Power Supply solutions: Regular breakdown of power supply has resulted in the failure of organic reactions as well as damage of electronic appliances. Therefore a need to establish backup of power supply. Expendable supplies Chemicals and solvents: These play key role in all reaction either organic or inorganic and no one can performed reaction without this so these funding are fully justified General Lab Expenditures: these are the basic need for researcher to meet day to day expenses Participation in local conferences, workshops and winter/summer schools by PI and students: These funding are required to communicate our work on national and international level. Also learn gain information from their experience

An Explication of Sylvia Plath8217s 8220Daddy8221 Essay -- essays pape

An Explication of Sylvia Plath8217s 8220Daddy8221 It tends to be the trend for women who have had traumatic childhoods to be attracted to men who epitomize their emptiness felt as children. Women who have had unaffectionate or absent fathers, adulterous husbands or boyfriends, or relatives who molested them seem to become involved in relationships with men who, instead of being the opposite of the â€Å"monsters† in their lives, are the exact replicas of these ugly men. Sylvia Plath’s poem â€Å"Daddy† is a perfect example of this unfortunate trend. In this poem, she speaks directly to her dead father and her husband who has been cheating on her, as the poem so indicates. The first two stanzas, lines 1-10, tell the readers that Plath, for thirty years, has been afraid of her father, so scared that she dares not to â€Å"breathe or Achoo.† She has been living in fear, although she announces that he’s already dead. It is obvious that she believes that her father continues to control her life from the grave. She says that she â€Å"has had to kill† him, but he’s already dead, indicating her initial promise to forget him. She calls him a â€Å"bag full of God,† telling us that she considers her father a very strong, omnipotent being, someone who is superior in her eyes. In the middle of the poem, she begins to refer to herself as a Jew, and her father the German, who began â€Å"chuffing me off like a Jew†¦to Dachau, Auschwitz, Belson.† What Plath’s intent here is to allow us to understand that her father was a German, and she relates his behavior as a person to a Nazi. But later, she becomes more enraged, and strips the title of God from her father, and labels him a swastika and a brute. â€Å"Every woman adores a Fascist† is Plath’s way of ... ...r husband were monsters in her life, destroying her, but that she has just noticed. â€Å"Daddy, daddy, you bastard, I’m through† is the last line in the poem. It is not until the end that we realize that not only is she through with the memories of her dead father and the adulterous behavior of her husband, but she is through with herself. This last line is clear – Plath has just announced to her readers that she will be committing suicide again, and plans on being successful at it. So, instead of this poem being Plath’s victorious confession to the horrible men in her life, and finally allowing closure, the poem is an outline of her promising death. Plath is still pained by these men, and cannot completely go on being alive. She believes that death is her only solution, and maybe in a way it was. Perhaps she is finally free, and finally able to â€Å"breath† and â€Å"Achoo.†

Corporate Social Responsibility Essay

In general, Corporate Social Responsibility can be described as an approach by which a company: * recognises that its activities have a wider impact on the society in which it operates and that developments in society in turn impact on its ability to pursue its business successfully. * actively manages the economic, social, environmental and human rights impact of its activities across the world, basing these on principles which reflect international values, reaping benefits both for its own operations and reputation as well as for the communities in which it operates. * seeks to achieve these benefits by working closely with other groups and organisations – local communities, civil society, other businesses and home and host governments. Corporate Social Responsibility (CSR) has been a critical part of the Sunway Group for the past three decades. Sunway Group company is one that instils and celebrates the culture of giving to society. The Group recognises the significance of developing and harnessing human capital excellence in driving the development and growth of the company, the community and our country. Winning the Anugerah PMCSR is a form of encouragement for The Group as it has truly brought CSR to an entirely new level. Sunway Group also has been recognised for outstanding achievements in CSR. The Sunway Group’s CSR programmes are wide-spread and aim to protect and promote human capital excellence above and beyond the company. In enhancing human capital excellence through education, if I the director of Sunway Group, I would implement the programmes which is: * Raising the level and standards of education in the country * Providing for the less fortunate members of the community. * Growing a healthy and sustainable knowledge-based workforce in Malaysia. The corporate social responsibility that Sunway Group provided are : 1) The Jeffrey Cheah Foundation The Sunway Education Trust Fund was established in March 1997 for the purpose of managing and administering surpluses from the institutions for the benefit of students be it for reinvestment into the institutions or for the disimbursement of scholarships and research grants. The Jeffrey Cheah Foundation was formed to perpetuate and crystallise the vision of a credible vehicle that will serve the cause of bringing good and quality education to the nation. Shares are transferred under the Sunway Education Trust into this Foundation where they will be held for perpetuity and can never be sold. Total profits from the Sunway University College and 70% of the profits from the Monash University Sunway Campus are ploughed back into activities to deliver higher quality education, to grow research capabilities and for the upgrading of facilities. From January to June 2010, more than RM4 million worth of scholarships were given out. 2) The Public School Adoption & Restoration Programme The Sunway Group has contributed to primary and secondary-level education schools over the last few years. Some of these projects have involved direct and active participation in restoration works, where the Group has dedicated consultancy, labour and construction resources into the refurbishment projects. In recent years, about RM3 million was contributed to schools such as SMK Bandar Sunway, SCK Chee Wen, SMK Klang Convent, the Gunung Hijau Primary School, SRK Bandar Sunway and SMJK Yuk Choy, Ipoh. To date, total contributions to public schools add up to RM10 million. 3) The Job Placement Programme Recognising that every person deserves a chance to feel a sense of belonging and purpose in society, the Sunway Group runs a Job Placement Programme endorsed by the Ministry of Education, Malaysia. Special needs students from the Sunway sponsored SMK Bandar Sunway are trained on basic work-related skills and ethics. Upon graduating, these students are presented with certificates of accomplishment to seek employment, where they are able to progress as independent members of society’s workforce. To date, the five-year old programme has helped a total of 58 special needs students. In 2010, the fifth batch of 10 students commenced their job placement at Sunway’s subsidiaries starting March 2010, and two were hired under the year’s Job Placement programme. 4) CSR Bowling Besides fostering education and life skills from an intellectual perspective, Sunway also embarks on education and skills in the physical sporting arena. This programme is for those aged between 14 and 22, and endeavours to train participants in the physical recreational sport of bowling Bowling training consists of one hour per week at the Sunway Pyramid Bowl for a total consecutive duration of 23 sessions. There are about 30 students in this programme who attended the Bowling Tournament 2010 on 21st September. To date the Sunway Group has trained about 150 special students. 5) The New Straits Times (NST) School Sponsorship Programme The programme was launched in August 2005 with the aim of bridging the urban-rural gap among the student population with regards to English language acquisition, information access and skills development. The group identified seven schools under Sunway’s CSR programme to receive complimentary copies of the NST everyday for one year commencing May 2010. The identified schools are SJK (C) Gunung Hijau, SMK Bandar Sunway, SRK Bandar Sunway, SMK Convent Klang, SRK Convent Klang, SJK (C) Chee Wen, Subang and SMK Tambun, Ipoh. Other CSR initiatives undertaken by the Sunway Group include the Tan Sri Jeffrey Cheah Distinguished Speaker Series and the Sunway Medical Centre Public Health Forums. The Sunway Group reaches out to people at different levels of society through its CSR activities and aims to enhance the learning experience in the classroom and beyond. The Group hopes to improve the standard of education, quality of life and ultimately leave a positive change in turning Malays ia into a high-income nation.

Native Americans in the United States and African American Cowboys

Tenzin Dolkar APUSH, DAY-2-2 TO WHOM AND TO WHAT EXTENT WAS THE AMERICAN WEST A LAND OF OPPORTUNITY 1865 – 1890 During the year of 1865 to 1890, the American’s west land was a land of economic development for Native American, white settlers from the east across the Mississippi farmers, miners, ranchers and as well as African American cowboys and immigrants for Irish and Chines, moving west for goal of economic achievement and their position for profit.First, the Native Americans people opened the way of exploitation of the west land naturel environment. The Dawes Act, which turned Indians into landowners and farmers and distributed 160 acres for farming, designed Indians as individual rather than a group of tribes. The railroad made their trip easier, which Pacific Railroad Act was passed in 186, law allowed construction of new transportation systems.The Act also provided grants of land and limited jobs for immigrants’ worker on railroad, especially Chines immigr ants worked for a lower wage and discovered millions of gold and silvers. The immigrants worked for a wealthy white settler in the west. Moreover, the railroad opened faster access for transportation for castles, miners and all the peoples, who were making money. Including the Homestead Act was passed; its offered 160 acres of land for any settlers live on the land for five or more years with little registration fees.It helped poor people to achieve economic business and farmers who needed more land, were permitted to purchase of up to 160 acres of land for $2. 50. The farmers took advantage of Westland by doing international market, which mostly depended on railroads for shipment. Even farmers had difficulties of weather conditions, the produced the agricultural business by the Bonanza farm. The farmers were hopes to getting rich soon.Together with the African American cowboys and cattle industry turned into a new marker as well. Because of Indians on to new reservation and the rai lroad opportunities bring them easier transportation anywhere in urban markets; without the railroads the new business were take a time to make money . In brief, west land was a place of a new beginning for people who were moving for seeking life and opportunities and hoping to get rich. The wealthy white settlers made the most profit in Westland.

buy custom The Impact of The Spanish and Portuguese Colonization essay

buy custom The Impact of The Spanish and Portuguese Colonization essay Spaniards great voyages of exploration led them to be the first colonizers of America. The Spaniards first settlement in Americas was at Santo Domingo in West Indies in 1496. This was after Columbus second voyage by his brother, Bartholomew. Within the next twenty years following the initial settlement, the Spaniards had conquered most of Central America, which acted as the bases for the conquest of the rest of Americas. Later on in 1518, Hernando Cortes left Cuba with 600 men, 17 horses, and 10 guns for Aztec empire in Mexico. In three years, the Aztec empire fell and led to establishment of the Spanish rule in central Mexico. In 1531, Francisco Pissarro obtained royal consent for expedition and left for Peru with180 men, 27 horses and 2 guns. By 1536, he was in control of the country. Its in Mexico that the Spaniards explored North America, though colonization didnt start here until 17th century. From Peru, they advanced to the Bolivian plateau and southwards towards Chile. By the end of the 16th century, the whole area from New Mexico and Florida in the North and to Chile and the Rio de la Plata in the south was under Spanish rule apart from Brazil. The first interest on Brazil by Portugal was inspired by the 1520s menace of the French encroachment. In 1530, Portugal sent Martin de Souza as a leader of colonizing expedition. Spanish conquest of the new worlds was driven by the gold, glory and gospel (the three Gs). In 1531, Portuguese made the first attempt at colonizing Brazil by sending five ships and several hundred colonists to Brazil under the command of Matin de Sousa. The colony was first planted on a little island of Sao Vicente, close to the present Santos. Here, they welcomed Ramalho and his family and subsequent colonies were established in quick succession. The main reason for Portugal interest in Brazil was sugar. Although the Portuguese law prohibited enslavement of Indians the colonists paid little heed and started the enslavement of the native as well as the importation of the Negroes from the Guinea coast. After a few years from the start of colonization, Brazil became the chief world supplier of sugar.The discovery of gold in Sao Paulo threatened to depopulate the settlements along the coast. Even Portugal sent gold seekers in large numbers. The military incursion and takeover of the Americas was followed closely by the spiritual change. The new religion from the west in the form of saints of the old world were introduced and imposed on the new colonies. This was followed by tremendous change. Christians recorded and circulated the Holy Scripture both orally and in written texts. The fifteenth advent of the printing press enhanced the popularity and the spread of these literally genre, sacred history and didactic guide for behaviors. The relation between the Spanish and Indian cultures was described as converging. In 1549, king of Portugal sailed to his new American colonies with three hundred and twenty officials, three hundred convict colonists and six Jesuits with the instructions of building a strong city t Bahia which was to become the seat of the government. After the establishment of their presence on the new land, the problem to effectively legislate and administer their new possessions arose. This also included the need to compile the ethnographical information of hundreds of different indigenous people. This led to chartering of the contratacion and the sea in 1503 by Ferdinand and Isabella. Its mandate was to manage private commerce and royal monopolies in the new world. This led to radical changes in the discipline of cosmography of addressing and adequately describing flora and fauna of the new world. This involved the exhaustive exercise of compilation and erudition which was to place the new world within the web of symbol and classical correspondence that was the Europeans understanding of the world. Also, the new cosmographers had to update the information of the new discoveries continually into the overall world picture. This led to the new routes in to Indies being officially endorsed. The new nautical chart, also known pardo n real (royal ratter).With time these cosmographers could determine the longitudinal location of a given location with precision. In addition, new instruments were discovered which made the Pacific Ocean and the general navigation easier. These instruments simplified the astronomical and mathematical computations that were necessary for determining the location at high seas. The arrival of the Spaniards and Portuguese in the new land brought with it new diseases in which the native Indians had no inbuilt immunity e.g. measles, smallpox, cholera and pneumonia.This led to massive revolution in the field of medicine. Recent literature brings to light how the new diseases introduced by the Europeans led to birth of a branch of medicine, (colonial medicine).The great limitation of receiving medicine from the west led to frequent exchanges and subsequent working together of Europeans, indigenous and African cultures. There was a change of the native Indians culture with the entrance of the colonizers. For example, the natives were present oriented while the colonizers were future oriented. For the natives, time was relative and they used seasons to keep track of time. On the other hand, the Europeans colonizers were time conscious and specific time was set aside for specific tasks. The indigenous were more oriented on giving while the Europeans were more about saving for tomorrow. For the natives, cooperation was the order of the day, but for the colonizers competition was the most important thing in mind. The Natives were in harmony with the nature and didnt try to change it. On the other hand, their Europeans counterparts believed on the conquest over nature and that people should modify their environment to make it more comfortable for their habitation. This great difference in their cultures had a greaat impact on the Native American people, some of whom changed and oriented their culture tow ards the European way of life while others, who wanted to preserve their culture, moved to areas unwanted by Europeans. Spaniards came with them paintings and pieces of furniture from Europe and typically tried to reproduce their fashions in their new territory. The arrival of the Spaniards and Portuguese led to massive migration as the lands were taken over. The different tribes which previously lived peacefully were forced to compete for food and this led to subsequent wars. Many tribes gave up farming and became nomadic pastoralist following the buffalo herds as they migrated between the plains. In addition, new crops were introduced in Latin America. Both maize and potatoes were introduced during Spanish colonization. They are staple foods today in most parts of Latin America. The Americas colonization also led to the widespread exportation of the indigenous knowledge of the Africans, Asians and Native Americans. During the Spanish rule, the Spanish dug countless sources of archives and curiosities and shipped it to Spain. The researchers claim that this was meant to deny any potential imperial rivals the much needed information about the loosely held frontiers. The Brooklyn exhibit organized by Diana Fane, Sarah Faunce and Kevin Staton, which concentrated on social implication of colonial arts-examining how both Spanish and the Indians struggled to find an identity, which honored their respective pasts and at the same time reflecting on their present, exhibited more than three hundred (300) works ranging from paintings, sculptures, textiles and religious objects. Most of these were from the Spanish viceroyalties of New Spain (1535-1821) and Peru (1542-1824), of which corresponded roughly to the geographic boundaries of the Aztec and Inca empires.It is in America that the new systems of governance were set which was in many respects the most advanced system of colonial control. In conclusion, the entrance and colonization of the Americas by the Spaniards and Portuguese caused more harm than good as indicated in most scholarly work available. Although it improved trade between the Portuguese, Brazil and the rest of the world, it led to increased importation of Negroes as slaves. According to these sources, Portuguese government from Brazil was not less than $ 10,000.000. Also, its estimated that at the end of the Portuguese Brazil there was about 1,500,000 Negro slaves. Buy custom The Impact of The Spanish and Portuguese Colonization essay

Software Engineering Essay

Software Engineering Essay Software Engineering Essay ORACLE ADF tutorial: Open a new application workspace. [pic] Change the application template to Web Application (Default).This allows us to specify the technology used in the application to simplify and personalize the environment according to the technology preferences. [pic] [pic] Open a Business Component diagram. [pic] [pic] Establish a connection to the Database and then select any two tables. In this case I have selected Departments and Employees tables. [pic] Drag and drop of database tables onto a UML diagram can be used to create different types of objects with the same user experience. [pic] This will generate the business component diagram with the relationships indicated in it. Select all and then right click. [pic] Now select Default Data Model Components which are business components that collect data and present it to the client. [pic] [pic] [pic] [pic] [pic] [pic] Open page flow editor which allows you to visually and declaratively define the flow of application. This can also be done by right clicking on the ViewController. Drag and drop a Data Page from the component palette onto the screen. [pic] Double click on the DataPage1 and then select dataPage1.uix to open a new UIX page. [pic] [pic] Now open the data controls and double click on AppDataModuleControl and do the following steps. All previously created business services are exposed in the Data Control